We just booked on the Panorama for January and it will be our second time on the Panorama, third time on the Mexican Riveria itinerary. We love it! It's always nice to go out of your home port but it's also just always been a good cruise. If you have never done a cruise out of California, one thing to know is that the sea days are not always warm. We've done it in May before and had a variety of cloudy/cool days and sunny/warm days.
The Panorama is beautiful and well laid out. It has a good variety of premium restaurants. We also had some of the best crew ever on our last Panorama cruise; I know that can change but I'm hopeful some of that will still be there! I don't have any experience with the room type you are looking at but we have had a cabin right under the galley/MDR before and it was pretty loud very early in the morning. I would bring ear plugs, just in case.