Depending on your starting time, I would do the shopping streets, ea Lijnbaan, first, those are more less deserted at night. End at Markthal for a bite and maybe getting some snacks.
Take a Canal cruise, or visit the Big Museums around Museum Square. The Rijksmuseum for the Nightwatch or The Van Gogh Museum. Next to the Gogh is the City Museum for modern art. Anne Frank house is also an option. All the musea are easily reached by public transport. Reservations for the Musea are recommended especially the Anne Frank house.
I am familiar with the location, not the hotel. Location wise it is perfect. Close to Public Transport, Jordaan district and the Museum district is just a couple of stops away. I have been in another Westcord hotel, they had a clean pleasant vibe.