my sister has the gift of opinionated gab. A bonafide no filter Felicia, knowing this is half the battle, dealing with it is another. I have resorted to using body language the she understands. When her inquisition becomes uncomfortable, I turn face her and stare. That's her cue, and usually works, if not I turn and walk away and since it's usually about her, she excuses herself and follows me. At the table I'll carefully lean over and whisper " you have something in between your teeth " (code) she either stops talking or excuses her self from company.