From the MSC website
MSC Cruises has announced the easing of boarding requirements from 1 October 2022, provided for in the health and safety protocol.
For all those embarking on the Mediterranean, Northern Europe, Red Sea, Caribbean and Antilles, the obligation of vaccination against Covid-19 will no longer be needed, even if it remains strongly recommended. In the same geographic regions citizens who are fully vaccinated (two doses of the vaccine or one dose of Johnson & Johnson) will no longer be required to submit a negative swab result, but it is still recommended.