We have had the same feeling doing our 32 day cruise. I'm lucky that we have a good friend that came over a couple times a week to water my poted outdoor plants. She also had a key to the house to check on things inside if need be. Our next door neighbor came over and kept the pool level up. We have a pool guy that came in once a week to clean the pool and a gardner who came in once a week to do the front lawn.
You can go to the post office and request they hold the mail longer then 30 days. I believe it has to be done in person.
Setup auto pay for some bills, Over paid on others.
Would defiinitely not drive. Fly then Uber or take a shuttle to the port. Parking at the port has gotten extremely expensive.